WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: gene_symbol, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_TATAAA_V$TATA_01       ID:DB_ID:2456
C=1276; O=20; E=1.86; R=10.73; rawP=9.20e-16; adjP=1.76e-13
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  LIF NA LIF leukemia inhibitory factor 3976 ENSG00000128342
2  CCL7 NA CCL7 chemokine (C-C motif) ligand 7 6354 ENSG00000108688
3  SELE NA SELE selectin E 6401 ENSG00000007908
4  NPPA NA NPPA natriuretic peptide A 4878 ENSG00000175206
5  S100A8 NA S100A8 S100 calcium binding protein A8 6279 ENSG00000143546
6  PENK NA PENK proenkephalin 5179 ENSG00000181195
7  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
8  DEFB1 NA DEFB1 defensin, beta 1 1672 ENSG00000164825
9  TGFB2 NA TGFB2 transforming growth factor, beta 2 7042 ENSG00000092969
10  RGS1 NA RGS1 regulator of G-protein signaling 1 5996 ENSG00000090104
11  MARCO NA MARCO macrophage receptor with collagenous structure 8685 ENSG00000019169
12  CSF3 NA CSF3 colony stimulating factor 3 (granulocyte) 1440 ENSG00000108342
13  TNMD NA TNMD tenomodulin 64102 ENSG00000000005
14  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
15  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558
16  MYH6 NA MYH6 myosin, heavy chain 6, cardiac muscle, alpha 4624 ENSG00000197616
17  IL1RN NA IL1RN interleukin 1 receptor antagonist 3557 ENSG00000136689
18  ESM1 NA ESM1 endothelial cell-specific molecule 1 11082 ENSG00000164283
19  S100A9 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
20  PPBP NA PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 5473 ENSG00000163736


Database:Transcription Target       Name:hsa_V$GATA4_Q3       ID:DB_ID:2178
C=246; O=8; E=0.36; R=22.26; rawP=2.95e-09; adjP=2.82e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  CXCL5 NA CXCL5 chemokine (C-X-C motif) ligand 5 6374 ENSG00000163735
2  LIF NA LIF leukemia inhibitory factor 3976 ENSG00000128342
3  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
4  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558
5  HOXA3 NA HOXA3 homeobox A3 3200 ENSG00000105997
6  CXCL6 NA CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 6372 ENSG00000124875
7  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
8  RGS1 NA RGS1 regulator of G-protein signaling 1 5996 ENSG00000090104


Database:Transcription Target       Name:hsa_V$TATA_01       ID:DB_ID:2025
C=255; O=7; E=0.37; R=18.79; rawP=9.71e-08; adjP=6.18e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  LIF NA LIF leukemia inhibitory factor 3976 ENSG00000128342
2  CCL7 NA CCL7 chemokine (C-C motif) ligand 7 6354 ENSG00000108688
3  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
4  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
5  NPPA NA NPPA natriuretic peptide A 4878 ENSG00000175206
6  RGS1 NA RGS1 regulator of G-protein signaling 1 5996 ENSG00000090104
7  GADD45G NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222


Database:Transcription Target       Name:hsa_V$GATA1_05       ID:DB_ID:2062
C=280; O=7; E=0.41; R=17.11; rawP=1.83e-07; adjP=8.74e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  CXCL5 NA CXCL5 chemokine (C-X-C motif) ligand 5 6374 ENSG00000163735
2  TGFB2 NA TGFB2 transforming growth factor, beta 2 7042 ENSG00000092969
3  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
4  RGS1 NA RGS1 regulator of G-protein signaling 1 5996 ENSG00000090104
5  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558
6  HOXA3 NA HOXA3 homeobox A3 3200 ENSG00000105997
7  CXCL6 NA CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 6372 ENSG00000124875


Database:Transcription Target       Name:hsa_V$MEF2_Q6_01       ID:DB_ID:2315
C=241; O=6; E=0.35; R=17.04; rawP=1.49e-06; adjP=5.69e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  LIF NA LIF leukemia inhibitory factor 3976 ENSG00000128342
2  HS3ST2 NA HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 9956 ENSG00000122254
3  MYH6 NA MYH6 myosin, heavy chain 6, cardiac muscle, alpha 4624 ENSG00000197616
4  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
5  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
6  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558


Database:Transcription Target       Name:hsa_V$AP1_Q6_01       ID:DB_ID:2301
C=262; O=6; E=0.38; R=15.68; rawP=2.41e-06; adjP=6.58e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  IL1RN NA IL1RN interleukin 1 receptor antagonist 3557 ENSG00000136689
2  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
3  CAPN6 NA CAPN6 calpain 6 827 ENSG00000077274
4  PTPRH NA PTPRH protein tyrosine phosphatase, receptor type, H 5794 ENSG00000080031
5  GADD45G NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
6  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558


Database:Transcription Target       Name:hsa_V$AP1_Q2       ID:DB_ID:1964
C=261; O=6; E=0.38; R=15.74; rawP=2.36e-06; adjP=6.58e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  HS3ST2 NA HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 9956 ENSG00000122254
2  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
3  IL1RN NA IL1RN interleukin 1 receptor antagonist 3557 ENSG00000136689
4  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
5  PTPRH NA PTPRH protein tyrosine phosphatase, receptor type, H 5794 ENSG00000080031
6  HOXA3 NA HOXA3 homeobox A3 3200 ENSG00000105997


Database:Transcription Target       Name:hsa_V$AP1_C       ID:DB_ID:1987
C=270; O=6; E=0.39; R=15.21; rawP=2.87e-06; adjP=6.85e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  HS3ST2 NA HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 9956 ENSG00000122254
2  CSF3 NA CSF3 colony stimulating factor 3 (granulocyte) 1440 ENSG00000108342
3  IL10 NA IL10 interleukin 10 3586 ENSG00000136634
4  NDP NA NDP Norrie disease (pseudoglioma) 4693 ENSG00000124479
5  CAPN6 NA CAPN6 calpain 6 827 ENSG00000077274
6  GADD45G NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222


Database:Transcription Target       Name:hsa_V$SRF_Q5_01       ID:DB_ID:2299
C=218; O=5; E=0.32; R=15.70; rawP=1.75e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  CXCL5 NA CXCL5 chemokine (C-X-C motif) ligand 5 6374 ENSG00000163735
2  TNMD NA TNMD tenomodulin 64102 ENSG00000000005
3  NPPA NA NPPA natriuretic peptide A 4878 ENSG00000175206
4  GADD45G NA GADD45G growth arrest and DNA-damage-inducible, gamma 10912 ENSG00000130222
5  CXCL6 NA CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 6372 ENSG00000124875


Database:Transcription Target       Name:hsa_V$CEBPDELTA_Q6       ID:DB_ID:2171
C=238; O=5; E=0.35; R=14.38; rawP=2.66e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  IL1RN NA IL1RN interleukin 1 receptor antagonist 3557 ENSG00000136689
2  DEFB1 NA DEFB1 defensin, beta 1 1672 ENSG00000164825
3  S100A9 NA S100A9 S100 calcium binding protein A9 6280 ENSG00000163220
4  PI15 NA PI15 peptidase inhibitor 15 51050 ENSG00000137558
5  HOXA3 NA HOXA3 homeobox A3 3200 ENSG00000105997




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).